Whole-Exome Sequencing Reveals High Mutational Concordance between Primary and Matched Recurrent Triple-Negative Breast Cancers

Whole-Exome Sequencing Reveals High Mutational Concordance between Primary and Matched Recurrent Triple-Negative Breast Cancers

Purpose: Triple-negative breast cancer (TNBC) is a molecularly complex and heterogeneous breast cancer subtype with distinct biological features and clinical behavior. Although TNBC is associated with an increased risk of metastasis and recurrence, the molecular mechanisms underlying TNBC metastasis...

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Bibliographic Details
Main Authors: Jaspreet Kaur, Darshan S. Chandrashekar, Zsuzsanna Varga, Bettina Sobottka, Emiel Janssen, Khanjan Gandhi, Jeanne Kowalski, Umay Kiraz, Sooryanarayana Varambally, Ritu Aneja
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Genes
Subjects:
triple negative breast cancer
tumor mutational burden
whole exome sequencing
Online Access:https://www.mdpi.com/2073-4425/14/9/1690

Internet

https://www.mdpi.com/2073-4425/14/9/1690

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