Qualitative assessment of healthy volunteer experience receiving subcutaneous infusions of high-dose benzathine penicillin G (SCIP) provides insights into design of late phase clinical studies

<h4>Introduction</h4> Secondary prophylaxis to prevent rheumatic heart disease (RHD) progression, in the form of four-weekly intramuscular benzathine benzylpenicillin G (BPG) injections, has remained unchanged since 1955. Qualitative investigations into patient preference have highlighte...

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Bibliographic Details
Main Authors: Stephanie L. Enkel, Joseph Kado, Thel K. Hla, Sam Salman, Julie Bennett, Anneka Anderson, Jonathan R. Carapetis, Laurens Manning
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138475/?tool=EBI