Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity

Compared to the overwhelming amount of literature describing how epithelial-to-mesenchymal (EMT) -inducing transcription factors orchestrate cellular plasticity in embryogenesis and epithelial cells, the functions of these factors in non-epithelial contexts, such as melanoma, are less clear. Melanom...

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Bibliographic Details
Main Authors: Niels eVandamme, Geert eBerx
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00352/full