Distribution of cholinergic nerve terminals in the aged human brain measured with [18F]FEOBV PET and its correlation with histological data

Distribution of cholinergic nerve terminals in the aged human brain measured with [18F]FEOBV PET and its correlation with histological data

Introduction: [18F]fluoroetoxybenzovesamicol ([18F]FEOBV) is a positron emission topography (PET) tracer for the vesicular acetylcholine transporter (VAChT), a protein located predominantly in synaptic vesicles in cholinergic nerve terminals. We aimed to use [18F]FEOBV PET to study the cholinergic t...

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Bibliographic Details
Main Authors: Niels Okkels, Jacob Horsager, Miguel A. Labrador-Espinosa, Frederik O. Hansen, Katrine B. Andersen, Mie Kristine Just, Tatyana D. Fedorova, Casper Skjærbæk, Ole L. Munk, Kim V. Hansen, Hanne Gottrup, Allan K. Hansen, Michel J. Grothe, Per Borghammer
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:NeuroImage
Subjects:
Brain
Cholinergic Neurons
VAChT Proteins
PET-CT
mRNA
Healthy Volunteer
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811923000563

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http://www.sciencedirect.com/science/article/pii/S1053811923000563

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