Aspirin minimized the pro-metastasis effect of sorafenib and improved survival by up-regulating HTATIP2 in hepatocellular carcinoma.

Aspirin minimized the pro-metastasis effect of sorafenib and improved survival by up-regulating HTATIP2 in hepatocellular carcinoma.

BACKGROUND AIMS: We previously demonstrated the pro-metastasis effect of sorafenib in hepatocellular carcinoma (HCC), which is mediated by down-regulation of tumor suppressor HTATIP2. The aim of the present study was to determine whether aspirin minimizes this effect and improves survival. METHODS:...

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Bibliographic Details
Main Authors: Lu Lu, Hui-Chuan Sun, Wei Zhang, Zong-Tao Chai, Xiao-Dong Zhu, Ling-Qun Kong, Wen-Quan Wang, Ke-Zhi Zhang, Yuan-Yuan Zhang, Qiang-Bo Zhang, Jian-Yang Ao, Jia-Qi Li, Lu Wang, Wei-Zhong Wu, Zhao-You Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669011?pdf=render

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http://europepmc.org/articles/PMC3669011?pdf=render

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