Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer

Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer

Abstract Background Unlike other breast cancer subtypes that may be treated with a variety of hormonal or targeted therapies, there is a need to identify new, effective targets for triple-negative breast cancer (TNBC). It has recently been recognized that membrane potential is depolarized in breast...

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Bibliographic Details
Main Authors: Gina Sizemore, Sarah McLaughlin, Mackenzie Newman, Kathleen Brundage, Amanda Ammer, Karen Martin, Elena Pugacheva, James Coad, Malcolm D. Mattes, Han-Gang Yu
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Cancer
Subjects:
Potassium channels
Hyperpolarization
Triple-negative breast cancer
Online Access:http://link.springer.com/article/10.1186/s12885-020-07071-1

Internet

http://link.springer.com/article/10.1186/s12885-020-07071-1

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