Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair

The earliest methods of genome editing, such as zinc-finger nucleases (ZFN) and transcription activator-like effector nucleases (TALENs), utilize customizable DNA-binding motifs to target the genome at specific loci. While these approaches provided sequence-specific gene-editing capacity, the labori...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Marlo K. Thompson, Robert W. Sobol, Aishwarya Prakash
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2021-06-01
Cyfres:Biology
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/2079-7737/10/6/530