Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair
The earliest methods of genome editing, such as zinc-finger nucleases (ZFN) and transcription activator-like effector nucleases (TALENs), utilize customizable DNA-binding motifs to target the genome at specific loci. While these approaches provided sequence-specific gene-editing capacity, the labori...
| Главные авторы: | , , |
|---|---|
| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
MDPI AG
2021-06-01
|
| Серии: | Biology |
| Предметы: | |
| Online-ссылка: | https://www.mdpi.com/2079-7737/10/6/530 |