Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria [version 1; referees: 2 approved]

Paroxysmal nocturnal hemoglobinuria (PNH) is a very rare disease that has been investigated for over one century and has revealed unique aspects of the pathogenesis and pathophysiology of a hemolytic anemia. PNH results from expansion of a clone of hematopoietic cells that, as a consequence of an in...

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Bibliographic Details
Main Author: Lucio Luzzatto
Format: Article
Language:English
Published: F1000 Research Ltd 2016-02-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-209/v1