TNFα induces matrix metalloproteinase-9 expression in monocytic cells through ACSL1/JNK/ERK/NF-kB signaling pathways

Abstract Studies have established the association between increased plasma levels of matrix metalloproteinase (MMP)-9 and adipose tissue inflammation. Tumor necrosis factor α (TNFα) was elevated in obesity and is involved in the induction of MMP-9 in monocytic cells. However, the underlying molecula...

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Bibliographic Details
Main Authors: Areej Al-Roub, Nadeem Akhter, Fatema Al-Rashed, Ajit Wilson, Fawaz Alzaid, Fahd Al-Mulla, Sardar Sindhu, Rasheed Ahmad
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41514-6