Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes

Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes

Liver diseases affect hundreds of millions of people worldwide; most often the hepatocytes or cholangiocytes are damaged. Diseases of the biliary tract cause severe patient burden, and cholangiocytes, the cells lining the biliary tract, are sensitive to numerous drugs. Therefore, investigations into...

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Bibliographic Details
Main Authors: Zhenguo Wang, João Faria, Luc J. W. van der Laan, Louis C. Penning, Rosalinde Masereeuw, Bart Spee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
intrahepatic cholangiocyte organoids
cholangiocytes
bioengineered bile duct
hollow fiber membrane
monolayer
polarity
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.868857/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.868857/full

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