Phenotyping of circulating extracellular vesicles (EVs) in obesity identifies large EVs as functional conveyors of Macrophage Migration Inhibitory Factor

Objective: Obesity-associated metabolic dysfunctions are linked to dysregulated production of adipokines. Accumulating evidence suggests a role for fat-derived extracellular vesicles (EVs) in obesity-metabolic disturbances. Since EVs convey numerous proteins we aimed to evaluate their contribution i...

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Bibliographic Details
Main Authors: Jérémy Amosse, Maëva Durcin, Marine Malloci, Luisa Vergori, Audrey Fleury, Frédéric Gagnadoux, Séverine Dubois, Gilles Simard, Jérôme Boursier, Olivier Hue, M. Carmen Martinez, Ramaroson Andriantsitohaina, Soazig Le Lay
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877818308585