Assessment of exercise-induced changes in von Willebrand factor as a marker of severity of aortic stenosis

BackgroundLoss of high-molecular-weight multimers (HMWMs) of von Willebrand factor (vWF) occurs due to high shear stress in patients with aortic stenosis. As symptoms of aortic stenosis occur during exercise, measurement of vWF during exercise might identify patients with aortic stenosis of clinical...

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Main Authors: Jo M Zelis, Frederik M Zimmermann, Froukje P J Andriessen, Patrick Houthuizen, Jop Van de Ven, Jolanda Leuverman, Nils P Johnson, Nico H J Pijls, Volkher Scharnhorst, Marcel Van 't Veer, Pim A L Tonino
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Open Heart
Online Access:https://openheart.bmj.com/content/7/1/e001138.full