Modified poly-L-lysine for use as a clearing agent in pretargeted radioimmunotherapy

Modified poly-L-lysine for use as a clearing agent in pretargeted radioimmunotherapy

Abstract Background Pretargeted radioimmunotherapy of cancer has the potential to increase tumor specific uptake of activity when compared with conventional radioimmunotherapy. This is especially true in radioimmunotherapy with nuclides that exhibit a relatively short half-life. When administering a...

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Bibliographic Details
Main Authors: Chiara Timperanza, Anna Gustafsson-Lutz, Tom Bäck, Damian J. Green, Sture Lindegren, Emma Aneheim
Format: Article
Language:English
Published: SpringerOpen 2024-11-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Pretargeted radioimmunotherapy
Pretargeting
Clearing agent
Poly-L-lysine
Streptavidin/avidin–biotin
Tetrazine-Transcyclooctene/TCO, Click chemistry
Online Access:https://doi.org/10.1186/s41181-024-00307-6

Internet

https://doi.org/10.1186/s41181-024-00307-6

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