The mechanosensitive Piezo1 channels contribute to the arterial medial calcification

The mechanosensitive Piezo1 channels contribute to the arterial medial calcification

Vascular calcification (VC) is associated with a number of cardiovascular diseases, as well as chronic kidney disease. The role of smooth muscle cells (SMC) has already been widely explored in VC, as has the role of intracellular Ca2+ in regulating SMC function. Increased intracellular calcium conce...

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Bibliographic Details
Main Authors: László Szabó, Norbert Balogh, Andrea Tóth, Ágnes Angyal, Mónika Gönczi, Dávid Máté Csiki, Csaba Tóth, Ildikó Balatoni, Viktória Jeney, László Csernoch, Beatrix Dienes
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Physiology
Subjects:
vascular smooth muscle
mechanosensation
Piezo1
calcification
intracellular calcium concentration
Yoda1
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1037230/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.1037230/full

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