LINE-1 and Alu methylation signatures in autism spectrum disorder and their associations with the expression of autism-related genes

LINE-1 and Alu methylation signatures in autism spectrum disorder and their associations with the expression of autism-related genes

Abstract Long interspersed nucleotide element-1 (LINE-1) and Alu elements are retrotransposons whose abilities cause abnormal gene expression and genomic instability. Several studies have focused on DNA methylation profiling of gene regions, but the locus-specific methylation of LINE-1 and Alu eleme...

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Bibliographic Details
Main Authors: Thanit Saeliw, Tiravut Permpoon, Nutta Iadsee, Tewin Tencomnao, Valerie W. Hu, Tewarit Sarachana, Daniel Green, Chanachai Sae-Lee
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18232-6

Internet

https://doi.org/10.1038/s41598-022-18232-6

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