Homogeneous production and characterization of recombinant N-GlcNAc-protein in Pichia pastoris

Homogeneous production and characterization of recombinant N-GlcNAc-protein in Pichia pastoris

Abstract Background Therapeutic glycoproteins have occupied an extremely important position in the market of biopharmaceuticals. N-Glycosylation of protein drugs facilitates them to maintain optimal conformations and affect their structural stabilities, serum half-lives and biological efficiencies....

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Bibliographic Details
Main Authors: Shengjun Wang, Yongheng Rong, Yaoguang Wang, Decai Kong, Peng George Wang, Min Chen, Yun Kong
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Microbial Cell Factories
Subjects:
Pichia pastoris
Endoglycosidase
N-GlcNAc-protein
Glycoprotein
Homogeneous protein production
Online Access:https://doi.org/10.1186/s12934-020-1280-0

Internet

https://doi.org/10.1186/s12934-020-1280-0

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