Analysis of β-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions

Analysis of β-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions

Abstract Background African Americans (AA) are at high risk for Colorectal Cancer (CRC). Studies report a 30–60% increase in CRC risk with physical inactivity, obesity and metabolic syndrome. Activation of the WNT/β-catenin (CTNNB1) signaling pathway plays a critical role in colorectal carcinogenesi...

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Bibliographic Details
Main Authors: Babak Shokrani, Hassan Brim, Tahmineh Hydari, Ali Afsari, Edward Lee, Mehdi Nouraie, Zaki Sherif, Hassan Ashktorab
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Gastroenterology
Subjects:
β-Catenin
Colorectal cancer
Advanced adenoma
African Americans
Online Access:http://link.springer.com/article/10.1186/s12876-020-01412-x

Internet

http://link.springer.com/article/10.1186/s12876-020-01412-x

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