Striatin translocates to the cytosol of apoptotic cells and is proteolytically cleaved in a caspase 3-dependent manner

Striatin translocates to the cytosol of apoptotic cells and is proteolytically cleaved in a caspase 3-dependent manner

Striatin (STRN) is a multivalent protein holding great therapeutic potentials in view of its interaction with dynamic partners implicated in apoptosis. Although striatin-3 and striatin-4, that share high structural similarities with STRN, have been linked to apoptosis, the dynamics of STRN in apopto...

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Bibliographic Details
Main Authors: Moni Nader, Bariaa Khalil, Wejdan Kattuah, Nduna Dzimiri, Dana Bakheet
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Heliyon
Subjects:
Cell biology
Cell culture
Cell death
Cytoskeleton
Membrane
Striatin, apoptosis, caspase 3, and proteolysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020318338

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http://www.sciencedirect.com/science/article/pii/S2405844020318338

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