Control of whole heart geometry by intramyocardial mechano-feedback: a model study.
Geometry of the heart adapts to mechanical load, imposed by pressures and volumes of the cavities. We regarded preservation of cardiac geometry as a homeostatic control system. The control loop was simulated by a chain of models, starting with geometry of the cardiac walls, sequentially simulating c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-02-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3276542?pdf=render |