A mini review of small-molecule inhibitors targeting palmitoyltransferases
Palmitoylation occurs when fatty acids (such as palmitic acid) create covalent bonds between cysteine, serine, threonine, or other residues in proteins. The downstream effect of palmitoylation depends on the protein being palmitoylated because its blockage can render the protein useless in terms of...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-08-01
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Series: | European Journal of Medicinal Chemistry Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417422000139 |