Biopharmaceutical Profiling of New Antitumor Pyrazole Derivatives

Biopharmaceutical Profiling of New Antitumor Pyrazole Derivatives

Several new pyrazole derivatives have demonstrated promising antiproliferative and cytotoxic effects, but their poor solubility raised concerns over possible biopharmaceutical limitations. In order to improve their pharmaceutical potential we performed the biopharmaceutical profiling for nine pyrazo...

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Bibliographic Details
Main Authors: Valentina Anuta, George Mihai Nitulescu, Cristina Elena Dinu-Pîrvu, Octavian Tudorel Olaru
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Molecules
Subjects:
acylthiourea
pyrazole derivatives
solubility
FaSSIF
FeSSIF
ADME prediction
Online Access:http://www.mdpi.com/1420-3049/19/10/16381

Internet

http://www.mdpi.com/1420-3049/19/10/16381

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