PARP Inhibition Sensitizes Breast Cancer Cells to Eribulin

Background: Poly(ADP-ribose) polymerases 1 and 2 (PARP1, 2), and 3 mediate protein modifications that facilitate the recruitment of DNA repair factors to single and double strand breaks. PARP3 is unique in that it is also required for efficient mitotic progression and stabilization of the mitotic sp...

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Bibliographic Details
Main Authors: Bahram Sharif-Askari, Lawrence Panasci, Raquel Aloyz
Format: Article
Language:English
Published: IMR Press 2023-03-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/28/3/10.31083/j.fbl2803052