Integrative Functional, Molecular, and Transcriptomic Analyses of Altered Intrinsic Timescale Gradient in Depression

Integrative Functional, Molecular, and Transcriptomic Analyses of Altered Intrinsic Timescale Gradient in Depression

The pathophysiology and pharmacology of depression are hypothesized to be related to the imbalance of excitation–inhibition that gives rise to hierarchical dynamics (or intrinsic timescale gradient), further supporting a hierarchy of cortical functions. On this assumption, intrinsic timescale gradie...

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Bibliographic Details
Main Authors: Shaoqiang Han, Ruiping Zheng, Shuying Li, Bingqian Zhou, Yu Jiang, Caihong Wang, Yarui Wei, Jianyue Pang, Hengfen Li, Yong Zhang, Yuan Chen, Jingliang Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Neuroscience
Subjects:
first-episode depression
gene expression profiling
fMRI
intrinsic timescale gradient
neurotransmitter
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.826609/full

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https://www.frontiersin.org/articles/10.3389/fnins.2022.826609/full

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