Regulating pyroptosis by mesenchymal stem cells and extracellular vesicles: A promising strategy to alleviate intervertebral disc degeneration

Regulating pyroptosis by mesenchymal stem cells and extracellular vesicles: A promising strategy to alleviate intervertebral disc degeneration

Intervertebral disc degeneration (IVDD) is a main cause of low back pain (LBP), which can lead to disability and thus generate a heavy burden on society. IVDD is characterized by a decrease in nucleus pulposus cells (NPCs) and endogenous mesenchymal stem cells (MSCs), degradation of the extracellula...

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Bibliographic Details
Main Authors: Sheng Yang, Yongbo Zhang, Qing Peng, Bo Meng, Jiabo Wang, Hua Sun, Liuyang Chen, Rui Dai, Liang Zhang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Low back pain
Intervertebral disc degeneration
Pyroptosis
Mesenchymal stem cells
Extracellular vesicles
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223017997

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http://www.sciencedirect.com/science/article/pii/S0753332223017997

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