S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis

S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis

Abstract Background Juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of conditions that can cause marked disability and diminished quality of life. Data on predictors of clinical response are insufficient to guide selection of the appropriate biologic agent for individual patients...

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Main Authors: Hermine I Brunner, Grant S Schulert, Alyssa Sproles, Sherry Thornton, Gabriel Vega Cornejo, Jordi Antón, Ruben Cuttica, Michael Henrickson, Ivan Foeldvari, Daniel J Kingsbury, Margarita Askelson, Jinqi Liu, Sumanta Mukherjee, Robert L Wong, Daniel J Lovell, Alberto Martini, Nicolino Ruperto, Alexei A Grom, on behalf of the Pediatric Rheumatology Collaborative Study Group (PRCSG) and the Paediatric Rheumatology International Trials Organisation (PRINTO)
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Arthritis Research & Therapy
Subjects:
Abatacept
Biomarkers
C-Reactive protein (CRP)
Juvenile idiopathic arthritis
S100
Online Access:https://doi.org/10.1186/s13075-024-03347-0

Internet

https://doi.org/10.1186/s13075-024-03347-0

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