Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL

Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a Notch3 dominant mutation-induced cerebral small vascular disease, is characterized by progressive degeneration of vascular smooth muscle cells (vSMCs) of small arteries in the brain, leading to re...

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Bibliographic Details
Main Authors: Xiao-Yun Liu, Maria E. Gonzalez-Toledo, Austin Fagan, Wei-Ming Duan, Yanying Liu, Siyuan Zhang, Bin Li, Chun-Shu Piao, Lila Nelson, Li-Ru Zhao
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Neurobiology of Disease
Subjects:
CADASIL
SCF
G-CSF
CAA
Vascular smooth muscle cell
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002782

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http://www.sciencedirect.com/science/article/pii/S0969996114002782

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