Piperine Attenuates Lithocholic Acid-Stimulated Interleukin-8 by Suppressing Src/EGFR and Reactive Oxygen Species in Human Colorectal Cancer Cells

Piperine Attenuates Lithocholic Acid-Stimulated Interleukin-8 by Suppressing Src/EGFR and Reactive Oxygen Species in Human Colorectal Cancer Cells

Piperine, a natural alkaloidal pungent product present in pepper plants, possesses the properties of anti-inflammatory and anti-metastasis. Lithocholic acid is a monohydroxy-5beta-cholanic acid with an alpha-hydroxy substituent at position 3; it is a secondary bile acid that plays a pivotal role in...

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Bibliographic Details
Main Authors: Shinan Li, Thi Thinh Nguyen, Trong Thuan Ung, Dhiraj Kumar Sah, Seon Young Park, Vinoth-Kumar Lakshmanan, Young Do Jung
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Antioxidants
Subjects:
piperine
interleukin-8
colorectal cancer
reactive oxygen species
tumor microenvironment
Online Access:https://www.mdpi.com/2076-3921/11/3/530

Internet

https://www.mdpi.com/2076-3921/11/3/530

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