Chemical Biology of Mammalian DNA Repair

Damage to the heterocyclic bases of DNA in the genome is mainly corrected by the base excision repair (BER) or nucleotide excision repair (NER) pathways. Base excision repair involves the sequential action of at least four enzymes and is initiated by DNA glycosylases. A lot of progress has...

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Bibliographic Details
Main Author: Orlando D. Schärer
Format: Article
Language:deu
Published: Swiss Chemical Society 2001-04-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/3417