SARS‐CoV‐2 innate effector associations and viral load in early nasopharyngeal infection

SARS‐CoV‐2 innate effector associations and viral load in early nasopharyngeal infection

Abstract COVID‐19 causes severe disease with poor outcomes. We tested the hypothesis that early SARS‐CoV‐2 viral infection disrupts innate immune responses. These changes may be important for understanding subsequent clinical outcomes. We obtained residual nasopharyngeal swab samples from individual...

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Bibliographic Details
Main Authors: Theodore G. Liou, Frederick R. Adler, Barbara C. Cahill, David R. Cox, James E. Cox, Garett J. Grant, Kimberly E. Hanson, Stephen C. Hartsell, Nathan D. Hatton, My N. Helms, Judy L. Jensen, Christiana Kartsonaki, Yanping Li, Daniel T. Leung, James E. Marvin, Elizabeth A. Middleton, Sandra M. Osburn‐Staker, Kristyn A. Packer, Salika M. Shakir, Anne B. Sturrock, Keith D. Tardif, Kristi J. Warren, Lindsey J. Waddoups, Lisa J. Weaver, Elizabeth Zimmerman, Robert Paine III
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Physiological Reports
Subjects:
biomarkers
host shut‐off
innate immunity
interferon
SARS‐CoV‐2
Online Access:https://doi.org/10.14814/phy2.14761

Internet

https://doi.org/10.14814/phy2.14761

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