Estimation of the allelic status of apolipoprotein E4 isoforms with fully automated LUMIPULSE® assays

Aim: Apolipoprotein E (ApoE) isoforms, especially the ApoE4 isoform, are genetic risk factors for Alzheimer’s disease (AD). Moreover, the APOE ε4 haplotype has a dose-dependent association with an increased risk of amyloid-related imaging abnormalities (ARIA) in individuals receiving disease-modifyi...

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Bibliographic Details
Main Authors: Tatsushi Yuri, Rosina Degrieck, Dagmara Minczakiewicz, Hideo Sato, Jo Kamada, Takuya Nakazawa, Ina Vandenbroucke, Katsumi Aoyagi, Hisashi Nojima
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2023-10-01
Series:Exploration of Neuroscience
Subjects:
Online Access:https://www.explorationpub.com/Journals/en/Article/100624