Alpha 5 Integrin Mediates Osteoarthritic Changes in Mouse Knee Joints.

Osteoarthritis (OA) is one of most common skeletal disorders and can affect synovial joints such as knee and ankle joints. α5 integrin, a major fibronectin receptor, is expressed in articular cartilage and has been demonstrated to play roles in synovial joint development and in the regulation of cho...

Full description

Bibliographic Details
Main Authors: Maria Elena Candela, Chao Wang, Aruni T Gunawardena, Kairui Zhang, Leslie Cantley, Rika Yasuhara, Yu Usami, Noelle Francois, Masahiro Iwamoto, Arjan van der Flier, Yejia Zhang, Ling Qin, Lin Han, Motomi Enomoto-Iwamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4900574?pdf=render