Tumor microenvironment complexity and therapeutic implications at a glance
Abstract The dynamic interactions of cancer cells with their microenvironment consisting of stromal cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to stimulate the heterogeneity of cancer cell, clonal evolution and to increase the multidrug resistance end...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12964-020-0530-4 |