Huaier polysaccharides suppress triple-negative breast cancer metastasis and epithelial-mesenchymal transition by inducing autophagic degradation of Snail

Huaier polysaccharides suppress triple-negative breast cancer metastasis and epithelial-mesenchymal transition by inducing autophagic degradation of Snail

Abstract Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, and the targeted therapies are lacking for this type of cancer. We previously demonstrated that Huaier effectively improve 5-year OS and DFS in stage III TNBC patients, and the polysaccharides o...

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Bibliographic Details
Main Authors: Yuan Tian, Jin Wu, Lingjuan Zeng, Linxi Zhou, Ying Hu, Qinwen Pan, Wei Liu, Yuzhao Yan, Ziwei Wu, Zhaoyu Wang, Zhen Zeng, Peng Tang, Jun Jiang, Minghao Wang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cell & Bioscience
Subjects:
Triple-negative breast cancer
Metastasis
Invasion
Huaier
In vitro
In vivo
Online Access:https://doi.org/10.1186/s13578-021-00682-6

Internet

https://doi.org/10.1186/s13578-021-00682-6

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