Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS

Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS

Background: Polycystic ovary syndrome’s (PCOS) main feature is hyperandrogenism, which is linked to a higher risk of metabolic disorders. Gene expression analyses in adipose tissue and skeletal muscle reveal dysregulated metabolic pathways in women with PCOS, but these differences do not necessarily...

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Bibliographic Details
Main Authors: Elisabet Stener-Victorin, Gustaw Eriksson, Man Mohan Shrestha, Valentina Rodriguez Paris, Haojiang Lu, Jasmine Banks, Manisha Samad, Charlène Perian, Baptiste Jude, Viktor Engman, Roberto Boi, Emma Nilsson, Charlotte Ling, Jenny Nyström, Ingrid Wernstedt Asterholm, Nigel Turner, Johanna Lanner, Anna Benrick
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
PCOS
adipose tissue
skeletal muscle
proteomics
transcriptomics
methylation
Online Access:https://elifesciences.org/articles/87592

Internet

https://elifesciences.org/articles/87592

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