Pyrrolyldihydropyrazino[1,2-a]indoletrione Analogue Microtubule Inhibitor Induces Cell-Cycle Arrest and Apoptosis in Colorectal Cancer Cells

Pyrrolyldihydropyrazino[1,2-a]indoletrione Analogue Microtubule Inhibitor Induces Cell-Cycle Arrest and Apoptosis in Colorectal Cancer Cells

In this study, 2-benzyl-10a-(1<i>H</i>-pyrrol-2-yl)-2,3-dihydropyrazino[1,2-<i>a</i>]indole-1,4,10(10a<i>H</i>)-trione (DHPITO), a previously identified inhibitor against hepatocellular carcinoma cells, is shown to exert its cytotoxic effects by suppressing the pr...

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מידע ביבליוגרפי
Main Authors:	Dong-Lin Yang, Hong-Xia Qin, Na-Na Zhang, Ya-Jun Zhang, Jiu-Hong Huang, Chun-Sheng Hu, Xiao-Xue Zhang, Yong Li, Liu-Jun He
פורמט:	Article
שפה:	English
יצא לאור:	MDPI AG 2023-02-01
סדרה:	Molecules
נושאים:	DHPITO colorectal cancer cells tubulin G2/M phase apoptosis cell migration
גישה מקוונת:	https://www.mdpi.com/1420-3049/28/4/1948

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