Lipid-mediated prestin organization in outer hair cell membranes and its implications in sound amplification

Prestin, a motor protein, plays a major role in sound amplification. Using molecular dynamics simulations, the authors show that prestin causes membrane deformation patterns thereby achieving a particular lipid-mediated alignment in the membrane.

Bibliographic Details
Main Authors: Sepehr Dehghani-Ghahnaviyeh, Zhiyu Zhao, Emad Tajkhorshid
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34596-9