Toxoplasma gondii ROP18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell P2X1

Toxoplasma gondii ROP18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell P2X1

Abstract Background Apoptosis plays a critical role in the embryonic development, homeostasis of immune system and host defense against intracellular microbial pathogens. Infection by the obligate intracellular pathogen Toxoplasma gondii can both inhibit and induce host cell apoptosis; however, the...

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Bibliographic Details
Main Authors: Li-Juan Zhou, Min Chen, Santhosh Puthiyakunnon, Cheng He, Jing Xia, Cynthia Y. He, Sheng-Qun Deng, Hong-Juan Peng
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Parasites & Vectors
Subjects:
Toxoplasma gondii
ROP18
Mitochondria
Apoptosis
P2X1
ATP
Online Access:http://link.springer.com/article/10.1186/s13071-019-3529-1

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http://link.springer.com/article/10.1186/s13071-019-3529-1

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