Optimizing Cardiac Out-Put to Increase Cerebral Penumbral Perfusion in Large Middle Cerebral Artery Ischemic Lesion—OPTIMAL Study

Optimizing Cardiac Out-Put to Increase Cerebral Penumbral Perfusion in Large Middle Cerebral Artery Ischemic Lesion—OPTIMAL Study

IntroductionIn unsuccessful vessel recanalization, clinical outcome of acute stroke patients depends on early improvement of penumbral perfusion. So far, mean arterial blood pressure (MAP) is the target hemodynamic parameter. However, the correlations of MAP to cardiac output (CO) and cerebral perfu...

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Bibliographic Details
Main Authors: Hannah Fuhrer, Albrecht Günther, Jan Zinke, Wolf-Dirk Niesen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neurology
Subjects:
acute stroke therapy
hemodynamics
cardiac output
cerebral perfusion
functional outcome
cerebral infarction
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00402/full

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http://journal.frontiersin.org/article/10.3389/fneur.2017.00402/full

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