H3K36 methyltransferase NSD1 is essential for normal B1 and B2 cell development and germinal center formation

B cells, which consist of two well-defined populations: B1 and B2 cells, which can produce antibodies that are essential for host protection against infections, through virus neutralization, opsonization and antibody-dependent cellular cytotoxicity. Epigenetic modifications, such as DNA methylation...

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Bibliographic Details
Main Authors: Sulan Zhai, Min Cao, Han Zhou, Huamin Zhu, Tongchang Xu, Yuliang Wang, Xiaoming Wang, Zhenming Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.959021/full