Pre-transplant gene profiling characterization by next-generation DNA sequencing might predict relapse occurrence after hematopoietic stem cell transplantation in patients affected by AML

Pre-transplant gene profiling characterization by next-generation DNA sequencing might predict relapse occurrence after hematopoietic stem cell transplantation in patients affected by AML

BackgroundIn the last decade, many steps forward have been made in acute myeloid leukemia prognostic stratification, adding next-generation sequencing techniques to the conventional molecular assays. This resulted in the revision of the current risk classification and the introduction of new target...

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Bibliographic Details
Main Authors: Elisabetta Metafuni, Viviana Amato, Sabrina Giammarco, Silvia Bellesi, Monica Rossi, Gessica Minnella, Filippo Frioni, Maria Assunta Limongiello, Livio Pagano, Andrea Bacigalupo, Simona Sica, Patrizia Chiusolo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
AML
stem cell transplant (SCT)
NGS
relapse
genes
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.939819/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.939819/full

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