Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals.

Tissue integrity and homeostasis often rely on the proliferation of stem cells or differentiated cells to replace lost, aged, or damaged cells. Recently, we described an alternative source of cell replacement- the expansion of resident, non-dividing diploid cells by wound-induced polyploidization (W...

Full description

Bibliographic Details
Main Authors: Vicki P Losick, Albert S Jun, Allan C Spradling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4784922?pdf=render