Effect of Chronic Western Diets on Non-Alcoholic Fatty Liver of Male Mice Modifying the PPAR-γ Pathway via miR-27b-5p Regulation

Effect of Chronic Western Diets on Non-Alcoholic Fatty Liver of Male Mice Modifying the PPAR-γ Pathway via miR-27b-5p Regulation

Western diets contribute to metabolic diseases. However, the effects of various diets and epigenetic mechanisms are mostly unknown. Here, six week-old C57BL/6J male and female mice were fed with a low-fat diet (LFD), high-fat diet (HFD), and high-fat high-fructose diet (HFD-HF) for 20 weeks. We dete...

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Bibliographic Details
Main Authors: Jian Zhang, Catherine A Powell, Matthew K Kay, Ravi Sonkar, Sunitha Meruvu, Mahua Choudhury
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
high-fat high-fructose diet
PPARγ
noncoding RNA
non-alcoholic fatty liver disease
obesity
diabetes
Online Access:https://www.mdpi.com/1422-0067/22/4/1822

Internet

https://www.mdpi.com/1422-0067/22/4/1822

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