The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies

The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies

Abstract Biomarkers sensitive to prodromal or early pathophysiological changes in Alzheimer’s disease (AD) symptoms could improve disease detection and enable timely interventions. Changes in brain hemodynamics may be associated with the main clinical AD symptoms. To test this possibility, we measur...

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Bibliographic Details
Main Authors: Timo Tuovinen, Janne Kananen, Zalan Rajna, Johannes Lieslehto, Vesa Korhonen, Riikka Rytty, Heli Mattila, Niko Huotari, Lauri Raitamaa, Heta Helakari, Ahmed Abou Elseoud, Johanna Krüger, Pierre LeVan, Osmo Tervonen, Juergen Hennig, Anne M. Remes, Maiken Nedergaard, Vesa Kiviniemi
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77984-1

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https://doi.org/10.1038/s41598-020-77984-1

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