The Impact of Mutational Hotspots on Cancer Survival

Background: Cofactors, biomarkers, and the mutational status of genes such as TP53, EGFR, IDH1/2, or PIK3CA have been used for patient stratification. However, many genes exhibit recurrent mutational positions known as hotspots, specifically linked to varying degrees of survival outcomes. Neverthele...

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Bibliographic Details
Main Authors: Melissa Gonzalez-Cárdenas, Víctor Treviño
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/5/1072