Identification of miRNA–mRNA Pairs in the Alzheimer’s Disease Expression Profile and Explore the Effect of miR-26a-5p/PTGS2 on Amyloid-β Induced Neurotoxicity in Alzheimer’s Disease Cell Model

Identification of miRNA–mRNA Pairs in the Alzheimer’s Disease Expression Profile and Explore the Effect of miR-26a-5p/PTGS2 on Amyloid-β Induced Neurotoxicity in Alzheimer’s Disease Cell Model

Alzheimer’s disease (AD) is a progressive neurodegenerative disease and the most common type of dementia. MicroRNAs (miRNAs) have been extensively studied in many diseases, including AD. To identify the AD-specific differentially expressed miRNAs and mRNAs, we used bioinformatics analysis to study c...

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Bibliographic Details
Main Authors: Tao Xie, Yongyan Pei, Peijia Shan, Qianqian Xiao, Fei Zhou, Liuqing Huang, Shi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
miRNA–mRNA
miR-26a-5p/PTGS2
neurotoxicity
baicalein
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.909222/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.909222/full

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