Obesity-mediated regulation of HGF/c-Met is associated with reduced basal-like breast cancer latency in parous mice.

Obesity-mediated regulation of HGF/c-Met is associated with reduced basal-like breast cancer latency in parous mice.

It is widely thought that pregnancy reduces breast cancer risk, but this lacks consideration of breast cancer subtypes. While a full term pregnancy reduces risk for estrogen receptor positive (ER+) and luminal breast cancers, parity is associated with increased risk of basal-like breast cancer (BBC)...

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Bibliographic Details
Main Authors: Sneha Sundaram, Alex J Freemerman, Joseph A Galanko, Kirk K McNaughton, Katharine M Bendt, David B Darr, Melissa A Troester, Liza Makowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4213021?pdf=render

Internet

http://europepmc.org/articles/PMC4213021?pdf=render

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