New Cocrystals of Ligustrazine: Enhancing Hygroscopicity and Stability

New Cocrystals of Ligustrazine: Enhancing Hygroscopicity and Stability

Ligustrazine (TMP) is the main active ingredient extracted from <i>Rhizoma Chuanxiong</i>, which is used in the treatment of cardiovascular and cerebrovascular diseases, with the drawback of being unstable and readily sublimated. Cocrystal technology is an effective method to improve the...

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Bibliographic Details
Main Authors: Yifei Xie, Lixiang Gong, Yue Tao, Baoxi Zhang, Li Zhang, Shiying Yang, Dezhi Yang, Yang Lu, Guanhua Du
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Molecules
Subjects:
ligustrazine
benzoic acid
cocrystal
stability
hygroscopicity
Online Access:https://www.mdpi.com/1420-3049/29/10/2208

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https://www.mdpi.com/1420-3049/29/10/2208

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