Structure-based design and construction of a synthetic phage display nanobody library
Abstract Objective To design and construct a new synthetic nanobody library using a structure-based approach that seeks to maintain high protein stability and increase the number of functional variants within the combinatorial space of mutations. Results Synthetic nanobody (Nb) libraries are emergin...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-03-01
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Series: | BMC Research Notes |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13104-022-06001-7 |