A predictive framework for integrating disparate genomic data types using sample-specific gene set enrichment analysis and multi-task learning.

Understanding the root molecular and genetic causes driving complex traits is a fundamental challenge in genomics and genetics. Numerous studies have used variation in gene expression to understand complex traits, but the underlying genomic variation that contributes to these expression changes is n...

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Bibliographic Details
Main Authors: Brian D Bennett, Qing Xiong, Sayan Mukherjee, Terrence S Furey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3441565?pdf=render